Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03622879Recruiting
Mirror therapy plus mild skin stimulation for leg movement after stroke
This trial tests whether using a mirror together with mild electrical stimulation on the skin can improve lower-limb movement after stroke. You may be eligible if you can already lift your ankle a bit and walk independently, and if certain thinking, vision, and skin issues are not present.
Hong KongAges 55–85 - NCT03626480Recruiting
Nutrition support before and after heart surgery for babies
This trial studies a nutrition plan given around the time of heart surgery for babies with congenital heart disease. It may help improve how babies grow and recover by supporting feeding before and after the operation.
Hangzhou, ZhejiangAges 1 day–1 year - NCT03628313Recruiting
Aortic Valve Narrowing: Long-term Outcomes Study
This study follows patients with aortic stenosis (a narrowing of the heart valve that controls blood flow from the heart) to understand how the condition progresses over time and what outcomes patients experience. By reviewing medical records and contacting patients for follow-up, researchers hope to better predict who is at higher risk and inform treatment decisions.
Amiens, FranceAges 18–100 - NCT03636295RecruitingPhase 3
Testing a lower INR goal to reduce bleeding in mechanical valves
This Phase 3 study tests whether aiming for a lower blood-thinning test result (INR) can reduce bleeding risk in people with a specific type of mechanical heart valve. The trial checks if this lower INR goal is safer while still protecting against dangerous clots.
Genk, LimburgAges 18 years+ - NCT03642509Recruiting
Compare a heart procedure to blood-thinner pills for stroke prevention
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
Aarhus, Central JutlandAges 18 years+ - NCT03646955Recruiting
Partial breast radiation versus no radiation after lumpectomy
This trial compares giving radiation only to part of the breast versus not giving radiation at all after breast-conserving surgery. It’s meant for women with early, hormone-driven breast cancer to see if skipping radiation can be safe and reduce treatment burden.
SantiagoAges 60 years+ - NCT03647852Recruiting
Study for difficult IgA vasculitis with gut symptoms
This study looks at treatment strategies for children with IgA vasculitis (also called Henoch-Schönlein purpura) when it mainly affects the stomach and intestines and symptoms do not improve with standard steroid dosing. It may help find better ways to control the illness early and prevent serious complications.
ShanghaiAges 2–16 - NCT03653156Recruiting
Aging and brain study for mild memory loss and dementia
This study checks how age affects memory and thinking, and compares people with mild memory problems, Alzheimer’s disease types, vascular dementia, and healthy controls. You may help researchers understand brain changes using thinking tests, MRI scans, and blood or spinal fluid tests.
Hefei, AnhuiAges 18 years+ - NCT03659708Recruiting
Study to prevent dangerous blood clots during pregnancy
This study looks at pregnancy-related risk for a dangerous blood clot in the leg or lung (venous thromboembolism). It focuses on pregnant people who already have a higher-than-average risk and wants to see how to manage that risk safely.
BronAges 18–50 - NCT03663348Recruiting
Patient registry for Takotsubo (stress) heart syndrome
This study is a patient registry that collects information from people diagnosed with Takotsubo syndrome, also known as a stress-related heart condition. It may help researchers learn more about who is affected and how the condition behaves over time.
New York, New YorkAges 18–110 - NCT03663777Recruiting
Hand strength training for women with poor leg blood flow
This trial tests whether guided handgrip (hand strength) exercises can improve health in post-menopausal women who have reduced blood flow to the legs. It may help your circulation and overall function, as long as you can safely do the training and keep your current medications during the study.
São Paulo, São PauloAges 45 years+ - NCT03670524Recruiting
HEAL Green Heart study for healthy community living
This study looks at health effects of changes in the local environment and community actions in Louisville. You may be able to join if you live in the right area and meet basic safety and health requirements.
Louisville, KentuckyAges 30–70 - NCT03676868Recruiting
Study of brain blood vessel malformations and outcomes
This study looks at how brain arteriovenous malformations (abnormal connections between arteries and veins in the brain) behave over time, and how different treatment choices affect outcomes. It may help researchers better predict prognosis and guide future care.
ParisAges birth+ - NCT03674788Recruiting
Heart valve patients getting a catheter procedure
This is a registry that follows people who are having a catheter-based treatment for a heart valve problem. It helps doctors understand how these procedures work in real life and may improve future care.
LeuvenAges Any age - NCT03680794Recruiting
Testing a blood and eye-fluid marker in retinal disease
This study looks at a specific lab marker (sCD160) in blood and eye fluids to see how it relates to poor blood flow in the retina. You may be asked for samples taken during eye surgery to help doctors understand the disease better.
ReimsAges 18 years+ - NCT03687580Recruiting
At-home laser treatment for diabetic foot ulcers
This trial tests whether an at-home low-level laser can help diabetic foot ulcers heal. You may be able to do treatments yourself or with a caregiver, but you must meet specific wound, circulation, and safety requirements.
Toronto, OntarioAges 18–95 - NCT03692598Recruiting
Transcatheter repair for leaky tricuspid valve during heart surgery
This trial studies a catheter-based repair to help fix a leaky tricuspid valve (regurgitation), especially when you’re also having another heart surgery. It aims to improve valve function and symptoms while tracking safety and outcomes.
AarhusAges 18–85 - NCT03697356RecruitingPhase 2
Rituximab plus VRD, then lenalidomide to treat Waldenstrom’s
This Phase 2 study tests a treatment plan that starts with rituximab plus VRD (bortezomib, and reduced-dose drugs in the VRD group), then uses lenalidomide for maintenance to help control Waldenstrom’s macroglobulinemia. It may help people who need treatment because their disease is measurable.
Busan, Sue-guAges 19 years+ - NCT03698149Recruiting
Brain-signal training for hand and speech control after disability
This study tests whether recording brain signals can help people regain better control of movements in the arms and help with speech. It may be an option for people with significant disability from certain nerve and brain conditions who can safely take part in brain-monitoring procedures.
San Francisco, CaliforniaAges 21 years+ - NCT03703947Recruiting
Testing blood and imaging biomarkers in abdominal aneurysm patients
This study looks at blood and/or scan markers to better understand abdominal aortic aneurysms (AAA). It may help doctors predict risks and guide follow-up or treatment choices.
Rotterdam, South HollandAges 18 years+ - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT03710902Recruiting
Mobile coaching to lower heart risk after stroke
This trial tests whether a mobile technology program can help people manage risk factors like high blood pressure after an ischemic stroke or a “mini-stroke” (TIA). It may help lower future cardiovascular risks by improving day-to-day control of these conditions.
HämeenlinnaAges 40 years+ - NCT03711539Recruiting
Exercise program study to help prevent clogged heart arteries
This trial studies whether lifetime endurance exercise is linked to a lower risk of coronary artery disease (clogged heart arteries). It may help explain which people benefit most from regular endurance activity and who may need different prevention steps.
EdegemAges 45–70 - NCT03711110Recruiting
Heart-protection plan for older people with certain cancers
This trial looks at strategies to help prevent heart and blood-vessel problems in people over 65 who have certain cancers. It may help by monitoring and treating heart risks early to lower the chance of future cardiovascular events.
Santiago de Compostela, A CoruñaAges 65 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.