Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07534917Recruiting
New Pacemakers and Heart Function Study
This study compares newer pacemaker types to see how well they work and how they affect your heart's pumping ability and valve function over a short period. You'll be monitored closely with heart imaging to understand which pacemaker performs best.
LondonAges 18 years+ - NCT07534462Recruiting
Heart pump and ultrasound heart function study
This study uses ultrasound (echocardiography) to see how the Impella 5.5 heart pump affects your heart's pumping ability, especially the right side. It might help doctors better understand and care for people who need this pump.
Rochester, New YorkAges 18 years+ - NCT07537868RecruitingPhase 2
Montelukast to reduce heart damage after heart attack
This study tests whether montelukast (a medication that reduces inflammation) can limit heart damage when given immediately after a sudden heart attack. Researchers will measure inflammation markers and heart injury to see if this drug helps patients recover better.
Al MansurahAges 30–75 - NCT07537296Recruiting
Heart Imaging Study After Heart Attack
This study uses advanced CT scans to take detailed pictures of your heart and blood vessels after a recent heart attack treated with stent placement. The goal is to better understand heart damage and predict long-term outcomes.
Nanjing, JiangsuAges 18 years+ - NCT07535268Recruiting
Heart rhythm ablation outcomes in minority patients
This registry tracks outcomes for racial and ethnic minority patients undergoing a specific type of heart rhythm treatment (ablation) for atrial fibrillation. The goal is to understand how well this treatment works across different populations.
New York, New YorkAges 18 years+ - NCT06749002Recruiting
Functional training for turning after stroke
This trial tests whether adding functional muscle training to turning-specific exercises helps people who have had a stroke turn more easily. It may benefit those who can walk with supervision and have no major memory or other neurological problems.
Islamabad, Punjab ProvinceAges 45–60 - NCT07529054Recruiting
Robot-Assisted Walking Training After Stroke
This trial tests whether a robotic device that helps guide your walking can improve mobility and function after a stroke. If you've had a stroke at least 3 months ago and have some difficulty walking, this training might help you regain strength and independence.
Gröbming, StyriaAges 18–80 - NCT07527715Recruiting
Heart MRI Study for Dilated Heart Muscle Disease
This research uses cardiac MRI scans and patient data to better predict outcomes in people with dilated cardiomyopathy—a condition where the heart's main pumping chamber becomes enlarged and weakened. Participating could help doctors improve how they care for similar patients in the future.
Jinan, ShandongAges 18 years+ - NCT07527156RecruitingPhase 4
Ketones through a nose tube for severe heart failure
This trial tests whether giving a special liquid diet (ketones) through a thin tube in your nose helps your heart pump better when it's severely weakened and not getting enough blood to your body. Ketones are an alternative fuel your body can use instead of glucose.
Prague, PragueAges 18 years+ - NCT07525518Enrolling by invitation
Okami Medical Device Patient Registry
This is a registry—a database that tracks patient outcomes—for people receiving Okami Medical devices. By joining, you help doctors understand how well these devices work and whether they're safe over time.
Aurora, ColoradoAges 18 years+ - NCT07527299Recruiting
Varipulse catheter study for persistent atrial fibrillation
This study tests a new catheter to treat persistent atrial fibrillation (a type of irregular heartbeat lasting more than 7 days but less than a year). It aims to isolate the pulmonary veins and superior vena cava to restore normal rhythm. Some participants may also receive a left atrial appendage occlusion device if needed.
Birmingham, AlabamaAges 18–80 - NCT07532174Recruiting
Blood-Cleaning Device During Heart Surgery
This trial tests a special blood-filtering device (Efferon LPS) used during heart surgery to reduce inflammation and improve recovery. The device removes harmful substances from your blood during the operation.
BarnaulAges 18 years+ - NCT07529782RecruitingPhase 1
Safety and Efficacy of HDP-101 in Relapsed or Refractory Multiple Myeloma
This trial tests a new drug called HDP-101 in patients with multiple myeloma that has come back or stopped responding to previous treatments. The study aims to find the safest and most effective dose and to see if this drug can help control the cancer.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT07529275Recruiting
iCover Stent Safety and Performance in Complex Aortic Aneurysm Repair
This trial tests a special covered stent (iCover) used during a minimally invasive procedure to repair complex abdominal aortic aneurysms—life-threatening bulges in the main artery in your belly. The stent helps keep important blood vessels open during the repair.
BonheidenAges 55 years+ - NCT07531251RecruitingPhase 4
Barth Syndrome Heart Treatment Study
This trial tests a medicine called elamipretide (4TAZ) in boys with Barth Syndrome, a genetic condition affecting the heart and muscles. The goal is to see if this medicine can help improve heart function and how the body uses energy.
Needham, MassachusettsAges 5–55 - NCT05523999Recruiting
Recognizing out-of-hospital cardiac arrest in emergency calls
This study looks at how emergency dispatchers and communication systems can better recognize when a person may be in cardiac arrest during ambulance call handling. It may help EMS teams act faster, potentially improving outcomes.
PontoiseAges 18 years+ - NCT05610865RecruitingPhase 1
Stem cell treatment for chronic diabetic foot ulcers
This Phase 1 study tests whether stem cells taken from fat tissue (after a small procedure) can help heal a long-lasting diabetic foot ulcer. It mainly aims to help ulcers that are limited to soft tissue and have good blood flow to the foot.
Lahore, Punjab ProvinceAges 20–60 - NCT07526766Recruiting
Exercise Program for Heart Artery Dissection and Fibromuscular Dysplasia
This study tests whether a supervised exercise program is safe and helpful for people who have had a spontaneous tear in a heart artery (SCAD) or fibromuscular dysplasia (a condition affecting blood vessel walls). The goal is to see if exercise can improve heart health after recovery from these conditions.
Jacksonville, FloridaAges 21–65 - NCT07530640RecruitingPhase 3
Statins to Help Children With Kawasaki Disease Heart Problems
This trial tests whether a cholesterol-lowering medication called atorvastatin can help children whose hearts were damaged by Kawasaki disease (a serious childhood illness that inflames blood vessels). The study may help reduce long-term heart complications.
ShanghaiAges 2–18 - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Stanford, CaliforniaAges 12–17 - NCT07528144Recruiting
Exoskeleton vs. Lead Apron for Surgeon Protection During Aortic Repair
This study compares a new exoskeleton device (a wearable support system) to standard lead aprons for protecting surgeons from radiation during endovascular aortic repair procedures—a minimally invasive surgery to fix problems in the main artery in the abdomen. The trial tests whether the exoskeleton provides better protection and comfort.
Szczecin, West Pomeranian VoivodeshipAges 35 years+ - NCT07531966Recruiting
Blood Vessel Problems After Kidney Transplant Treatment
This study looks at treating narrowing or blockage of blood vessels in transplanted kidneys. If your transplanted kidney is showing signs of not working well and imaging shows a blocked vessel, this trial tests whether a procedure called angioplasty (opening the vessel with a tiny balloon) can help restore blood flow and improve kidney function.
AarhusAges 18 years+ - NCT07530588Recruiting
Remote CT imaging for fast stroke treatment decisions
This study tests whether CT scans done remotely (by doctors at a distance) can help stroke patients receive clot-busting treatment faster. Stroke treatment works best when given quickly, and this approach aims to speed up diagnosis in areas far from major hospitals.
SandnessjøenAges 18 years+ - NCT07528781Recruiting
New 3D Ultrasound Method for Measuring Heart Valve Leakage
This study tests a new way to measure leakage in the mitral valve (a valve in your heart) using advanced 3D ultrasound. If you have moderate or severe mitral valve leakage, this research may help doctors better understand and treat the condition.
Badalona, BarcelonaAges 18–95
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.