Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03787745Recruiting
Testing a heart-protection method after a blocked-artery procedure
This study looks at whether “ischemic postconditioning” (briefly changing blood flow right after opening a blocked heart artery) can improve outcomes in people with a specific type of heart attack. It’s meant for patients who get primary PCI (a catheter-based procedure to reopen the artery) soon after symptoms start.
CopenhagenAges 18 years+ - NCT03784651Recruiting
How breast cancer treatment changes metabolism and bone
This study looks at how standard breast cancer treatments affect your body’s metabolism and bones in postmenopausal people with early-stage breast cancer. It may help doctors better predict and prevent bone and metabolic side effects from treatment.
Copenhagen, DanmarkAges 50–70 - NCT03788512Recruiting
Registry study for recent stroke/TIA with heart artery disease
This study enrolls people who recently had an ischemic stroke or a TIA (a “mini-stroke”) and also have evidence of narrowed heart arteries. It collects information to better understand how brain and heart artery disease occur together and may guide future care.
Beijing, BJAges 18–85 - NCT03789916RecruitingPhase 3
Aspirin alone versus two blood thinners after heart bypass
This Phase 3 trial compares two strategies to prevent blood clots after heart bypass surgery: aspirin alone versus aspirin plus ticagrelor. It aims to see which approach works better and is safer for people whose bypass does not fully restore blood flow.
RomeAges 18 years+ - NCT03789552RecruitingPhase 3
Testing T89 to prevent chest pain during stable angina
This Phase 3 trial tests whether T89 reduces angina (chest pain caused by heart-related reduced blood flow) in people with stable angina. You may help confirm the treatment’s benefit by completing symptom tracking and exercise heart tests over several weeks.
Naples, FloridaAges 18–90 - NCT03790943Recruiting
Health study of heart problems in childhood cancer survivors
This study follows people who had cancer as children to learn about heart-related changes years after treatment. It may help doctors better understand who is at risk and how to monitor the heart in long-term survivors.
Basel, Canton of Basel-CityAges 18 years+ - NCT03791970Recruiting
Compare stent post-dilation using drug balloon or regular balloon
This study looks at whether using a drug-coated balloon (DCB) versus a regular balloon (POBA) right after placing a stent works better in artery blockages in the thigh/knee area. It may help improve blood flow and reduce the chance the artery narrows again.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT03794531Recruiting
Study of health, stress, and lifestyle changes in Puerto Rico
This study looks at how people’s health, day-to-day stress, and living conditions in Puerto Rico change over time. You might help researchers understand what trends are happening and what could be improved.
San JuanAges 30–75 - NCT03797183Recruiting
Check heart and lung function using a painless chest scan
This study uses a noninvasive scan that measures electrical signals across the chest to better understand breathing and heart-related circulation problems. It may help doctors learn what to monitor and how conditions like lung/airway pressure and vessel narrowing progress.
Aurora, ColoradoAges 2 weeks–40 years - NCT03799653Recruiting
Nurse health study for public hospital nurses in Xiamen
This study asks public hospital nurses in Xiamen to share health information over time. It may help researchers understand nurses’ well-being and work-related health needs, so better support can be developed.
Xiamen, FujianAges 20 years+ - NCT03807128Recruiting
Study for multiple myeloma resistance and relapse changes
This study looks at how multiple myeloma (a bone marrow cancer) changes over time, especially why it becomes resistant to treatment or comes back. It may help researchers learn what drives relapse and could lead to better future treatments.
La Roche-sur-YonAges 18 years+ - NCT03806283Recruiting
Study how pregnancy blood vessels change in late pregnancy
This study looks at how blood vessels adapt during late pregnancy, especially around the time of a C-section. Your participation may help researchers understand normal pregnancy changes and how they differ in certain complications.
Madison, WisconsinAges 18–40 - NCT03813862Recruiting
Study tracking medicines from clinic records
This is an observational study that collects information about what medicines patients receive. It uses data already recorded in participating clinics’ computer health records to better understand medication use over time.
Durham, North CarolinaAges birth+ - NCT03820492Recruiting
Testing imaging tools to assess a narrowed left main artery
This trial compares different heart scans to decide how serious a narrowing is in the left main coronary artery. It may help doctors choose the safest and most accurate way to manage that blockage during a heart catheter procedure.
Clermont-FerrandAges 18 years+ - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Tucson, ArizonaAges 18–70 - NCT03821051Recruiting
Registry for heartbeat rhythm problems from structural heart disease
This is a registry that collects information about people with certain dangerous heartbeat rhythm problems caused by structural (anatomical) heart diseases. It may help researchers understand patterns and risks, and improve how these conditions are studied and managed.
Beijing, Beijing MunicipalityAges Any age - NCT03821623RecruitingPhase 2
Vitamin-like nicotinamide riboside for higher blood pressure
This trial tests whether nicotinamide riboside can improve elevated blood pressure and blood vessel stiffness in middle-aged and older adults. You may be randomly assigned to take the study medicine or not, and the team will check your heart/blood vessel measurements over time.
Boulder, ColoradoAges 50 years+ - NCT03822949Recruiting
Bright light exposure during heart surgery for better recovery
This trial tests whether using bright light at the right time during and after heart surgery helps patients recover more comfortably. It focuses on people having a specific type of open-heart surgery and checks certain heart rhythm and safety factors.
Denver, ColoradoAges 18–90 - NCT03823547Recruiting
Research study for adults with ACS
This study is for adults who are being seen for ACS, to help improve future care. You may be invited to join if you can provide informed consent.
Apeldoorn, GelderlandAges 18 years+ - NCT03823534RecruitingPhase 3
Study pain control after preventive femur bone surgery
This Phase 3 study tests a pain medicine plan used after preventive surgery to place a metal rod inside the thigh bone (femur) before a fracture happens. The goal is to find an approach that controls post-surgery pain while being safe for the right patients.
St Louis, MissouriAges 18 years+ - NCT03826524RecruitingPhase 4
Finding the best epinephrine dose after EMS-treated cardiac arrest
This study compares two epinephrine doses during the emergency treatment of out-of-hospital cardiac arrest. It aims to find a dose that works better and more safely for people who are in a shockable heart rhythm when paramedics arrive.
Victoria, British ColumbiaAges 18 years+ - NCT03826264Recruiting
Research registry for people getting TAVR
This is a research registry that collects information about people who receive TAVR, a procedure to help open a narrowed heart valve. It may help doctors understand outcomes and improve care, but it is not designed as a drug or device trial by itself.
Stanford, CaliforniaAges 19 years+ - NCT03827187Recruiting
Brain signal training to detect awareness
This study checks whether brain activity patterns can show when a person is aware, even if they can’t reliably communicate. If signs of awareness are found (or if you already know you are aware), the study may also train a brain-computer interface to support communication or movement assistance.
DublinAges 10–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.