Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07530640RecruitingPhase 3
Statins to Help Children With Kawasaki Disease Heart Problems
This trial tests whether a cholesterol-lowering medication called atorvastatin can help children whose hearts were damaged by Kawasaki disease (a serious childhood illness that inflames blood vessels). The study may help reduce long-term heart complications.
ShanghaiAges 2–18 - NCT07531784Recruiting
Blood Test to Detect Heart Rejection After Transplant
This Swedish study tests whether a simple blood test can detect early signs that your body is rejecting a transplanted heart. The test looks for DNA fragments in your blood that may signal rejection before symptoms appear, potentially helping doctors catch problems sooner.
StockholmAges 18 years+ - NCT07529834Recruiting
Breathing and Cycling for High Blood Pressure
This study tests whether combining special breathing techniques (Pilates and diaphragmatic breathing) with moderate cycling exercise can help lower blood pressure and improve lung function in people with high blood pressure. You'll practice these techniques over several weeks to see if they reduce your blood pressure more effectively than exercise alone.
IslamabadAges 20–55 - NCT07526350RecruitingEarly Phase 1
MTS109 for Hard-to-Treat Autoimmune Diseases
This early-stage trial tests a new treatment called MTS109 for autoimmune diseases (like lupus, muscle inflammation, scleroderma, vasculitis, or Sjögren's syndrome) that haven't responded well to standard medications. The goal is to see if MTS109 can help control disease that keeps flaring or getting worse despite current treatments.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07525310Recruiting
Light therapy for blood pressure in people taking losartan
This study tests whether a special light therapy (called photobiomodulation) applied to your arms can help lower blood pressure and improve how your blood vessels work. It is for people who already take blood pressure medicine and have their blood pressure under control.
São Paulo, São PauloAges 18–65 - NCT07532733Recruiting
Sedation Safety During Minimally Invasive Heart Valve Procedure
This study examines how a specific sedative medication (dexmedetomidine) affects breathing and heart function during a minimally invasive procedure to replace a faulty heart valve. Researchers want to ensure the sedation is safe and effective for older adults.
BrusselsAges 60 years+ - NCT07526766Recruiting
Exercise Program for Heart Artery Dissection and Fibromuscular Dysplasia
This study tests whether a supervised exercise program is safe and helpful for people who have had a spontaneous tear in a heart artery (SCAD) or fibromuscular dysplasia (a condition affecting blood vessel walls). The goal is to see if exercise can improve heart health after recovery from these conditions.
Jacksonville, FloridaAges 21–65 - NCT07525635RecruitingEarly Phase 1
Finding the Right Aspirin Dose During Pregnancy
This study helps doctors figure out the best dose of aspirin for pregnant people at high risk of preeclampsia (a serious pregnancy complication with high blood pressure). Researchers will check how aspirin affects your blood and baby to keep you both safe.
New York, New YorkAges 18–50 - NCT07529691Recruiting
Physical Activity and Quality of Life in Fibromuscular Dysplasia
This study asks people with fibromuscular dysplasia (an artery condition) about their physical activity and how they're doing in daily life. The information helps doctors understand how the condition affects people's wellbeing and exercise ability.
Nashville, TennesseeAges 18–100 - NCT07531602Enrolling by invitation
How breathing pressure affects heart function during surgery
This study observes how different levels of breathing support during heart surgery affect your heart's function. Researchers will use ultrasound and monitoring tools already planned for your surgery to see how small changes in breathing pressure impact your heart's performance.
Boston, MassachusettsAges 18 years+ - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Stanford, CaliforniaAges 12–17 - NCT07526987RecruitingPhase 3
Minocycline to Help Recovery After Acute Stroke Treatment
This study tests whether an antibiotic called minocycline, given alongside standard stroke treatment (clot-busting medication), can help reduce brain damage and improve recovery. You would receive minocycline around the time of your clot-busting treatment.
Liaocheng, ShandongAges 18–80 - NCT07527117Recruiting
CT scan study for diagnosing sudden blood clots in lungs
This research study tests a special chest CT scan to help diagnose acute pulmonary embolism—a blood clot that suddenly blocks blood flow in your lungs. You may qualify if you're already getting a CT scan for suspected lung clots and meet basic health requirements.
Boston, MassachusettsAges 21 years+ - NCT07529821Recruiting
Breathing and Walking Exercise for Early High Blood Pressure
This study tests whether combining special breathing techniques with treadmill walking can help lower blood pressure and improve breathing function in people with slightly elevated blood pressure. If you have early-stage high blood pressure, this trial might help you avoid needing medication.
IslamabadAges 20–55 - NCT06385834Recruiting
Morning vs Evening Exercise After Heart Attack
This study compares the effects of doing aerobic exercise in the morning versus the evening for people who recently had a heart attack. It aims to see if timing of exercise can help the heart recover and function better.
ShanghaiAges 17–75 - NCT06588231Recruiting
Personalized exercise for older adults with heart disease
This study tests whether a personalized exercise program can help older people (60–75) with stable coronary heart disease improve their heart health. You would work with healthcare professionals to get an exercise plan tailored to your condition.
Nanjing, JiangsuAges 60–75 - NCT06744244Recruiting
Smell test for newborns with birth asphyxia
This study tests whether a simple smell test can help doctors better understand the risk of brain injury in newborns who had oxygen loss at birth. It may help identify babies who need extra monitoring without requiring cooling treatment.
ParmaAges 6 hours–3 days - NCT06753591Recruiting
Premature heart attack registry in Serbia
This trial is creating a registry of young adults (45 and under) who have had a heart attack. It will collect information to help doctors better understand and treat early heart attacks.
BelgradeAges 18–45 - NCT06753006Recruiting
Research on stroke rehabilitation for arm weakness
This study tests a new rehabilitation program for people who have had a stroke within the last 6 months. It focuses on improving arm weakness using special therapy techniques.
Samara, Samara OblastAges 18–80 - NCT07522203Recruiting
Heart Function Recovery After Balloon Angioplasty for Lung Blood Clots
This study looks at how a minimally invasive procedure called balloon pulmonary angioplasty (BPA) helps patients with chronic blood clots in the lungs improve their heart function and overall recovery. Researchers will measure blood flow patterns in your arteries before and after the procedure to understand how well your heart recovers.
IstanbulAges 18–85 - NCT07524998Recruiting
Surgery outcomes for complex heart defects across ages
This study tracks how children and adults with complex heart defects fare after surgery. Researchers want to understand what surgical techniques work best at different ages and how patients recover long-term.
BeijingAges Any age - NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
Minneapolis, MinnesotaAges 18 years+ - NCT07523750Recruiting
Pulsed field ablation for persistent atrial fibrillation
This study tests two types of pulsed field ablation catheters to treat persistent atrial fibrillation, a heart rhythm problem lasting more than 7 days but less than a year. The goal is to see if these catheters can safely and effectively restore a normal heart rhythm.
Jonesboro, ArkansasAges 18–80 - NCT07523555RecruitingPhase 1/Phase 2
Dual-Target CAR-T Cells for Blood Cancers That Haven't Responded to Treatment
This study tests a new type of cell therapy called CAR-T cells that are designed to target two different proteins on cancer cells. These cells are made from your own immune cells, trained in the lab, and then put back into your body to fight blood cancers that have come back or stopped responding to previous treatments.
Shenzhen, GuangdongAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.