Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03830320RecruitingPhase 1
PET scan to look for blood clots in the heart or lungs
This Phase 1 study uses a PET scan to detect blood clots (thrombosis) in specific groups of people. It’s testing how well the scan can find clots and how it should be timed with other heart or illness tests.
Boston, MassachusettsAges 18–85 - NCT03836521Recruiting
Registry for valve replacement in bicuspid aortic stenosis patients
This registry collects information about adults with severe narrowing of the aortic valve caused by a bicuspid (two-leaflet) valve shape, especially if symptoms are present. It may help doctors better understand who benefits from a catheter-based valve replacement (TAVR).
Los Angeles, CaliforniaAges 19–129 - NCT03846297Recruiting
Decision support for defibrillator placement in hypertrophic cardiomyopathy
This trial looks at how to make better decisions about whether someone with hypertrophic cardiomyopathy (HCM) should get an implantable heart defibrillator. It may help by using structured decision support to guide defibrillator implantation.
Boulogne-Billancourt, Hauts-de-SeineAges 16 years+ - NCT03845036Recruiting
Diet and exercise study for leg circulation problems
This study looks at how diet changes and an exercise program may improve walking and leg symptoms in people with peripheral artery disease (PAD). You may be eligible if you have a history of claudication (leg pain with walking) and tests or treatment history show PAD.
Oklahoma City, OklahomaAges 40 years+ - NCT03845946Recruiting
CLOUD-R HAE registry for hereditary angioedema patients
This registry study collects information from people with hereditary angioedema (swelling episodes) and related types, with or without a C1-related blood condition. It may help doctors better understand different patterns of swelling and improve future care.
Grenoble, IsereAges Any age - NCT03850015Recruiting
Ultrasound test to assess heart disease using faster images
This trial studies whether a newer, faster ultrasound imaging method can better assess areas of the heart that may not get enough blood during stress. You may be eligible if you have known coronary artery disease or are considered low risk, and if you can safely undergo the stress ultrasound test.
Harrow, MiddxAges 18 years+ - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT03852407RecruitingPhase 2
Two kinds of conditioning before matched stem cell transplant
This trial compares two reduced-intensity conditioning regimens before you receive stem cells from a donor who matches your HLA type. It aims to find which approach works better and is safer for certain blood cancers.
AntwerpAges 18–75 - NCT03855592Recruiting
Cancer patients with blood clots: thrombosis and cancer registry
This study is a registry that collects information about blood clot events in people with cancer. The goal is to better understand how often clots happen and what patterns they follow, which can help improve care.
Alcoy, AlicanteAges 18 years+ - NCT03858205Recruiting
Low-dose radiation to relieve pain from bone tumors
This trial studies whether low-dose radiation can reduce pain from a specific bone lesion caused by multiple myeloma. It may help people whose main problem is painful bone metastasis, with targeted treatment to the painful spot.
Duarte, CaliforniaAges 18 years+ - NCT03857529Recruiting
Rehab training for stroke arm control using brain and hand stimulation
This study tests whether non-invasive brain stimulation plus a hand/arm electrical stimulation device can improve how well your stroke-affected arm and hand move during therapy tasks. You would take part in screening and then receive these combined rehab approaches to see if motor control improves.
Cleveland, OhioAges 21 years+ - NCT03858777Recruiting
Blood test for heart inflammation in sarcoidosis
This study checks whether a blood “cell-free DNA” test can show when the heart is inflamed in people with cardiac sarcoidosis. It may help doctors detect active heart involvement earlier and track how disease is doing.
Iowa City, IowaAges 18 years+ - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+ - NCT03880708Recruiting
Registry for inherited dangerous heart rhythm conditions
This study is a heart rhythm registry for people with inherited conditions that can cause abnormal heart beats. By collecting health and testing information, researchers hope to better understand these conditions and improve care.
Beijing, Beijing MunicipalityAges 1 hour–90 years - NCT03881345Recruiting
Registry for blood clots in legs or lungs
This registry collects information from people who have a blood clot in a leg or a clot in the lung. It helps researchers understand how these conditions are treated in real life.
Moscow, MoscowAges 18 years+ - NCT03883711Recruiting
Study of treatment and outlook after heart attack
This trial studies how people do after a heart attack (or related heart injury) and may test treatments that could improve outcomes. If you’re an adult and recently had this heart event, you may be able to join after discussing consent.
Bologna, BolognaAges 18 years+ - NCT03885635Recruiting
Compare two surgeries for type 1 aortic dissection
This trial compares two different surgical approaches for adults who need emergency surgery for a specific kind of torn aorta (type 1 aortic dissection). It may help your surgical team choose the safest, most effective operation for people with your anatomy and health status.
London, OntarioAges 18–70 - NCT03891160Recruiting
Using heart scans to plan a support pump in children
This trial is testing a way to help doctors assess babies and children with congenital heart disease and heart failure before placing a temporary heart support pump. It may help improve planning by using heart scans to decide who needs support and how to prepare.
Gainesville, FloridaAges Any age - NCT03892174Recruiting
Removing inflammatory signals during heart surgery for endocarditis
This study tests whether removing certain inflammation signals (cytokines) can help people with severe heart infection (infective endocarditis) who are having heart surgery soon. It may help reduce harmful inflammation around the time of surgery, but it also has several medication and health-condition requirements.
BernAges 18 years+ - NCT03895541Recruiting
Test MRI/ultrasound to measure heart stiffness in older heart failure
This study checks whether a noninvasive imaging test can measure how stiff (stiffness) your heart muscle is in older people with certain types of heart failure. It may help doctors better diagnose and sort out the type of heart failure using your scan results.
ParisAges 60–80 - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Birmingham, AlabamaAges 18 years+ - NCT03908463Recruiting
Heart procedure registry for people who get coronary angioplasty
This trial is a registry that collects health information from adults who undergo a heart procedure called coronary angioplasty. It may help researchers understand outcomes and improve care for future patients undergoing similar treatments.
SeoulAges 19 years+ - NCT03909412RecruitingPhase 1
Carfilzomib chemo to help you collect stem cells for transplant
This Phase 1 study tests a carfilzomib-based treatment plan to help people with multiple myeloma collect enough stem cells for an autologous (using your own) stem cell transplant. It’s mainly about whether this mobilization approach works and is safe for you.
Hackensack, New JerseyAges 18 years+ - NCT03912324Recruiting
CT-guided heart imaging to guide treatment for atrial fibrillation
This trial studies whether using a special CT scan map of the heart muscle thickness can help doctors choose the best strategy during a cryoballoon procedure for paroxysmal atrial fibrillation. It may help improve effectiveness by tailoring treatment instead of using a standard approach.
SeoulAges 20–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.