Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07518030Recruiting
Telemedicine support for heart failure medication adjustment
This study tests whether remote check-ins via phone or video can help safely increase heart failure medications to target doses. You'll use a device to share weight, blood pressure, and heart rate with your doctor, who will adjust your medicines based on how you're doing.
PiacenzaAges 18 years+ - NCT07523646RecruitingPhase 4
Blood Boost for Patients With Heart Valve Infections
This study tests whether giving iron and a blood-boosting medicine (EPO) helps patients with bacterial heart valve infections who have low red blood cells. The goal is to see if it speeds recovery and improves how patients feel.
CopenhagenAges 18 years+ - NCT07524036Recruiting
Nursing education to help stroke patients follow care plans
This study tests whether a special nursing education session helps stroke patients stick to their recovery plan after going home. The goal is to see if personalized teaching improves how well patients take medications and follow doctor's advice.
BayonneAges 18 years+ - NCT07520656Recruiting
Heart Valve Surgery and Sleep Breathing Problems
This study looks at whether fixing heart valve problems with minimally invasive procedures (TAVI or MTEER) can improve sleep-related breathing issues. Researchers will monitor your sleep patterns before and after your scheduled heart valve procedure.
Athens, AtticaAges 18 years+ - NCT07521800Recruiting
Remote Heart Monitoring After Aortic Valve Replacement
This study tests whether monitoring your heart rhythm at home using a portable ECG device after your aortic valve replacement procedure (TAVI) helps catch problems early. Researchers want to see if remote monitoring is safe and helpful for patients recovering from this procedure.
TurinAges 18 years+ - NCT07521436Recruiting
Understanding Heart Disease Risk Awareness in Men and Women
This study asks people who have had heart or blood vessel problems about their understanding of risk factors and how they view their cardiovascular health. Researchers want to learn whether men and women perceive their heart disease risk differently.
MilanAges 18 years+ - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07520045Recruiting
Eye Injections for Diabetic Vision Loss: Two Treatment Comparison
This study compares two injectable medications (faricimab and biosimilar ranibizumab) used to treat diabetic retinopathy, a serious eye condition that can cause vision loss in people with diabetes. The trial will measure how well each medication works and track specific markers in your eye to understand treatment response.
OsijekAges 18 years+ - NCT07519876Recruiting
Blood Clots in the Lungs and Heart Shunts Study
This study looks at whether people with blood clots in their lungs have hidden holes in their hearts that let blood bypass normal circulation. Researchers will use imaging tests to understand this connection and see if it affects how patients do.
Boston, MassachusettsAges 18 years+ - NCT07516522RecruitingPhase 2
Steroid injection during stroke clot removal surgery
This trial tests whether injecting a steroid (methylprednisolone) directly into brain blood vessels after removing a stroke clot helps reduce brain swelling and improve recovery. You would be eligible if you had a large clot stroke in the front part of your brain that was successfully removed within the past 24 hours.
Xi'an, ShaanxiAges 18–80 - NCT06493994Recruiting
Looking at Myval valve placed through the armpit
This study collects information on people who have already received a new aortic valve through a small cut in their armpit using the Myval valve. Doctors want to see how well this approach works over time.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06657911Recruiting
Studying a new sizing method for bicuspid aortic valves
This trial looks back at people with a specific type of bicuspid aortic valve (a valve with two flaps instead of three) who had a transcatheter aortic valve replacement. Researchers want to see how well a special sizing method called LIRA worked for choosing the right valve size.
Brescia, ItalyAges 18 years+ - NCT06754475Recruiting
Low volume arm HIIT for heart failure patients
This trial tests if short, high-intensity arm exercises can help people with stable heart failure. It looks at safety and improvements in daily function.
Mersin, MersinAges 18 years+ - NCT06757049Recruiting
Using the Edwards MITRIS RESILIA valve in Asian patients
This study looks at how well a new mitral valve (the Edwards MITRIS RESILIA) works in people of Asian descent. It aims to see if this valve is safe and effective for patients who need mitral valve replacement.
Seoul, SONGPA-GUAges 19 years+ - NCT06756282Recruiting
Pacemaker use one year after TAVR
This study looks at people who need a permanent pacemaker after having a TAVR procedure (a type of heart valve replacement). It aims to see how many people still need the pacemaker one year later.
MontpellierAges Any age - NCT05544864Recruiting
Stent or balloon treatment guided by heart scar pattern
This study looks at how to treat blocked heart arteries that have narrowed again after a prior drug-eluting stent. It compares using another drug-eluting stent versus a drug-coated balloon, chosen based on an imaging scan inside the artery (OCT), to reduce repeat narrowing.
Frankfurt am Main, HesseAges 18 years+ - NCT04137549Recruiting
Monitoring nighttime blood pressure to reach target levels
This registry study looks at how well people can control high blood pressure during sleep. It may help your care team understand what changes support safer nighttime blood pressure targets.
Shanghai, Shanghai MunicipalityAges 50–79 - NCT05089448RecruitingPhase 4
Morning vs bedtime blood pressure medicine dosing study
This trial tests whether taking your blood pressure medicine in the morning or at bedtime controls blood pressure better over a full day and night. It may help certain people find a dosing time that improves nighttime blood pressure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06153563Recruiting
Mitral valve elasticity study during replacement
This trial measures the stretchiness (elasticity) of the mitral valve during surgery in people who are having it replaced. It helps doctors understand how valve stiffness relates to heart health.
Saint-EtienneAges 45 years+ - NCT03547856Recruiting
Registry study for blood pressure control in adults
This study collects health information to understand how well people with high blood pressure (who take blood pressure medicines) reach their blood pressure targets. It may help improve future guidance on blood pressure monitoring and control.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05943821RecruitingPhase 3
Allopurinol to lower heart and stroke risks in high-risk people
This trial studies whether allopurinol can reduce the chance of cardiovascular events like heart attack, stroke, or related problems in people who are at higher risk. It targets people with higher uric acid and other risk factors, to see if lowering uric acid helps protect the heart.
Poznan, WielkopolskaAges 40–70 - NCT05858944Recruiting
Home blood pressure program for people with high readings
This trial tests whether a home blood pressure–focused program helps improve blood pressure control in older adults. You may be asked to measure your blood pressure at home for at least several days and attend follow-up visits.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT06301412RecruitingPhase 3
Cooling plus clot removal for acute stroke
This trial tests whether cooling the body down (hypothermia) combined with a clot removal procedure (thrombectomy) helps people recover better from a large-artery stroke. You may be eligible if you have a moderate-to-severe stroke and can be treated within 24 hours of when you were last seen well.
Freiburg im BreisgauAges 18 years+ - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.