Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT06758921Recruiting
Testing a catheter for leg artery blockages
This study tests a special catheter to open blocked arteries in the thigh, knee, or lower leg. It may help improve blood flow and reduce symptoms like leg pain or wounds.
GrazAges 18 years+ - NCT06759181RecruitingPhase 1/Phase 2
CAR-T targeting BCMA and FcRL5 for relapsed/refractory myeloma
This trial tests a new type of immunotherapy called CAR-T cells that target two proteins (BCMA and FcRL5) on myeloma cells. It is for people whose myeloma has returned or not responded to other treatments.
XuzhouAges 18–70 - NCT06759103Recruiting
Study of patients with aortic coarctation
This study collects information from people diagnosed with aortic coarctation before or shortly after birth, to better understand the condition and improve care. It may be a fit if you or your child were diagnosed before or within one month of birth.
BolognaAges Any age - NCT06758648Recruiting
Eye blood vessels in Fabry disease
This study looks at the tiny blood vessels in the eyes of people with Fabry disease using a special camera. It may help doctors understand how the disease affects the eyes over time.
München, BavariaAges 18 years+ - NCT04142866Recruiting
Brain stimulation plus language practice for chronic aphasia
This study tests whether mild brain stimulation (tDCS) combined with language exercises can improve communication after a stroke. It also includes healthy volunteers to help compare brain and language task results.
New York, New YorkAges 21–80 - NCT07511361RecruitingPhase 2
Tonlamarsen for high blood pressure after hospitalization
This study tests an investigational medication (Tonlamarsen) for people who were recently hospitalized for a very severe high blood pressure episode and also have heart or kidney disease. It aims to see if the drug can help control blood pressure after discharge.
Arvada, ColoradoAges 18 years+ - NCT07510412Recruiting
NuShield plus standard care for venous leg ulcers
This trial tests a new wound covering called NuShield, used with standard care, to help heal leg ulcers caused by poor vein circulation. It may be an option if your ulcer hasn't healed after standard treatment.
Pickerington, OhioAges 18 years+ - NCT07510438Recruiting
Pulse IVL treatment for hardened arteries in the heart
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries, making them easier to open. It may help people with coronary artery disease who have not had prior stents or recent heart attacks.
Sydney, New South WalesAges 18 years+ - NCT07507903Recruiting
Aktiia blood pressure monitor safety and performance study
This trial tests a new wrist device that takes blood pressure readings regularly. The results are compared between when you first use it and a week later.
Broomfield, ColoradoAges 22–59 - NCT07515599Recruiting
Study of blood pressure medicine for nighttime control
This study watches how well Olmetec (a blood pressure medicine) controls your blood pressure, especially at night. Researchers will use a special monitor you wear for 24 hours to measure your blood pressure patterns and see if the medicine is working.
SeoulAges 19 years+ - NCT07509658Recruiting
TriClip device safety and performance study in Japan
This study will track how well the TriClip device works and its safety in people who are already eligible to receive it under its approved use. It helps make sure the device performs as expected in real-world patients.
Suita, OsakaAges Any age - NCT07508007Recruiting
Study on improving Lp(a) testing in heart clinics
This trial tests ways to help doctors check for high Lp(a), a risk factor for heart disease, in patients who need it. The study looks at whether special strategies increase testing rates in cardiology centers that currently test less than 15% of eligible patients.
NurembergAges 18 years+ - NCT06758713RecruitingPhase 1
Gene-therapy treatment for blood cancers: safety and early effects
This trial tests a new kind of gene therapy (fourth-generation CAR-T) for several types of blood cancers including lymphoma, leukemia, and myeloma. It aims to see if the treatment is safe and starts to work against the cancer.
Guangzhou, GuangdongAges 18–75 - NCT07508891Recruiting
Studying heart failure types in hospitalized patients
This trial looks at different types of acute heart failure in people who are hospitalized. Doctors will study your symptoms and health to better understand heart failure patterns, which might help improve future treatments.
HamburgAges 18 years+ - NCT07508618RecruitingPhase 4
Qidong Yixin Granule for preventing atrial fibrillation after ablation
This trial tests whether a traditional Chinese medicine granule, Qidong Yixin, can help prevent atrial fibrillation from coming back after a heart ablation procedure. It is for people with persistent atrial fibrillation who have not had good results from other heart rhythm medications.
HangzhouAges 18–80 - NCT07515508Recruiting
Understanding heart failure patterns in hospitalized patients
This study investigates different types of acute heart failure in hospitalized patients to better understand their condition and improve treatment. Researchers will use multiple imaging and testing methods to create a detailed picture of each patient's heart failure.
Bad KrozingenAges 18 years+ - NCT07514962Recruiting
Minimally invasive heart bypass surgery with a blood-thinner medication
This trial tests whether a blood-thinner drug called cangrelor helps patients who are having a special type of bypass surgery that uses a small incision instead of opening the whole chest. The surgery connects a healthy artery from your chest wall directly to a blocked heart vessel to restore blood flow.
Lugano, Ch/tiAges 18 years+ - NCT07507500RecruitingPhase 4
Comparing blood thinners and treatment length after a heart attack
This trial compares two common blood-thinning medications (prasugrel vs ticagrelor) and two treatment durations (short 1–3 months vs standard 12 months) after a heart attack treated with stents. It aims to find the most effective and safest anti-clotting strategy for patients.
DublinAges 18 years+ - NCT07512830Recruiting
Using Hypnosis to Help During Heart Ultrasound
This study tests whether hypnosis (guided relaxation) can help patients feel more comfortable and less anxious during a heart ultrasound procedure that looks at the heart from inside the throat. The goal is to see if it reduces discomfort and the need for sedating medications.
Paris, Île-de-France RegionAges 18 years+ - NCT07514052Recruiting
Predicting Response to Selinexor Treatment in Relapsed Multiple Myeloma
This study tests whether doctors can predict which patients with relapsed or hard-to-treat multiple myeloma will respond well to a drug called selinexor. Researchers will collect blood and bone marrow samples to identify markers that help personalize treatment decisions.
Taiyuan, ShanxiAges 18 years+ - NCT07515040Recruiting
AccuSafe guidewire versus needle for heart rhythm procedure
This trial compares two different tools used during a minimally invasive heart procedure to treat atrial fibrillation (an irregular heartbeat). The study tests whether a newer guidewire tool is safer and works as well as the traditional needle approach.
Nanchang, JiangxiAges 18–75 - NCT07509645RecruitingPhase 3
Testing a new drug with clot removal for severe back-of-the-brain stroke
This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.
Huaibei, AnhuiAges 18 years+ - NCT07508930Recruiting
Russian extreme high triglycerides registry
This study creates a registry for people with very high triglycerides (≥10 mmol/L). It aims to understand who gets this condition and how it affects them over time.
AstrakhanAges Any age - NCT07513974Recruiting
Pain sensitivity test to predict opioid needs in heart surgery
This study measures how sensitive you are to pain using a special device, then tracks how much pain medication you need during heart surgery. The goal is to see if pain sensitivity can predict opioid requirements and help doctors customize pain control for you.
Brussels, AnderlechtAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.