Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03998852RecruitingPhase 3
PET study of brain chemical changes in stroke apathy
This Phase 3 trial uses special brain scans (PET) to understand what brain chemical systems are involved in apathy after stroke. Your results may help researchers better understand the cause of apathy and guide future treatments.
BordeauxAges 18–75 - NCT03994874RecruitingPhase 1/Phase 2
Testing fluid removal through the belly in heart-kidney failure
This trial studies a treatment that removes extra fluid through a catheter placed in the abdomen (peritoneal ultrafiltration) for people with “cardio-renal syndrome” (heart and kidney problems together). It may help those who stay congested despite high-dose water pills (diuretics) and have certain heart circulation and fluid signs.
ChietiAges 18 years+ - NCT03995238Recruiting
Gait training for veterans with leg amputations
This study tests a walking rehabilitation plan to improve how you walk after a lower-leg amputation. It may help if your walking steps are uneven and you have diabetes and/or circulation problems in your legs.
Aurora, ColoradoAges 40–89 - NCT04000061Recruiting
Tracking heart failure and heart attack progress in hospital
This study looks at how heart problems progress while you’re in the hospital, using your medical information (clinical data). It may help doctors better predict outcomes and improve care for people with heart attacks and heart failure.
BaselAges 18 years+ - NCT03998319RecruitingPhase 3
Testing low-dose clot-busting drug after heart attack stent
This trial tests whether a low-dose clot-busting medicine placed into the heart artery after a primary stent can improve outcomes in people with a certain type of heart attack. It also involves short hospital follow-ups and a heart MRI to look at how the heart is recovering.
Bankstown, New South WalesAges 18 years+ - NCT03999983Recruiting
Procedure registry for blocked vertebral artery origins
This trial registry collects information on patients treated with a catheter-based procedure for narrowed or blocked vertebral artery openings in the back of the brain. It may help doctors better understand which patients benefit and how treatment is done, but it’s mainly about tracking outcomes and safety.
Jacksonville, FloridaAges 18–90 - NCT04005508Recruiting
Study sleep apnea and heart outcomes in high-risk atrial fibrillation
This trial looks at how obstructive sleep apnea (OSA, a breathing problem during sleep) relates to heart outcomes in people with atrial fibrillation (AF). It may help doctors better predict risk and choose safer care for people who are high cardiovascular risk.
SingaporeAges 22–99 - NCT04005469RecruitingPhase 1/Phase 2
Treprostinil to protect kidneys during transplant injury
This early-phase study tests whether treprostinil (Remodulin®) can reduce injury to a transplanted kidney right after surgery. If it works and is safe, it may help improve outcomes for people receiving a deceased-donor kidney transplant.
Providence, Rhode IslandAges 18–75 - NCT04005976Recruiting
Genetic study for inherited aortic disease
This trial is for people with inherited (family-run) aortic enlargement or aneurysm caused by a specific DNA gene change. It uses genetic information to guide more precise care, which may help tailor monitoring and treatment for you and your family.
Newport Beach, CaliforniaAges Any age - NCT04006535Recruiting
Genetic testing study for vasculitis in families and children
This study uses a detailed DNA test to look for possible genetic causes of vasculitis (inflammation of blood vessels) in children and adults. It may help researchers better understand why vasculitis happens, especially in families.
Paris, Île-de-France RegionAges Any age - NCT04130503Recruiting
Breathing device study after a recent ischemic stroke
This study looks at whether using a PAP breathing machine soon after an ischemic stroke helps sleep and recovery. It focuses on people who have moderate to severe obstructive sleep apnea diagnosed around the time of their stroke.
New Haven, ConnecticutAges 18 years+ - NCT06580002RecruitingPhase 2
Can Riluzole Help with Chemo Brain? A Pilot Study
This study tests if a medicine called riluzole (currently used for ALS) can help with 'chemo brain' – memory and thinking problems after cancer treatment. It is for people who feel their mental sharpness has declined after breast cancer therapy, certain chemotherapies, or brain radiation.
Orange, CaliforniaAges 18 years+ - NCT07492524Recruiting
Better care for older adults with AF and heart failure in rural China
This trial tests a new way to manage care for older patients with atrial fibrillation and heart failure living in rural areas. It uses village doctors and telemedicine to help monitor and treat these conditions together.
Yancheng, DongtaiAges 65–80 - NCT07701512RecruitingPhase 2
Febuxostat for brain bleed patients managed without surgery
This trial tests if febuxostat, a medicine used for gout, can help people recover from a brain bleed (intracranial hemorrhage) when surgery is not needed. It may reduce inflammation and improve outcomes.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07701590Recruiting
New wound dressings for hard-to-heal leg and foot ulcers
This study tests a special amniotic membrane wound dressing compared to a synthetic wound matrix for stubborn diabetic foot ulcers or venous leg ulcers. It may help if your wound has not been healing well for over a month.
San Diego, CaliforniaAges 18 years+ - NCT07702149Recruiting
Diet for Behcet's disease patients with ringing in the ears
This trial tests whether a special diet can help ringing in the ears (tinnitus) in people with Behcet's disease who also have obesity. The goal is to see if dietary changes reduce tinnitus symptoms.
Giza, DokkiAges 40–55 - NCT06728826Recruiting
Preventing atrial fibrillation after heart surgery with pericardiotomy
This study tests if opening the sac around the heart (pericardiotomy) can lower the chance of developing an irregular heartbeat called atrial fibrillation after heart surgery. It is for people having surgery on the heart's valves, major blood vessels, or arteries.
ShanghaiAges 18 years+ - NCT07702123Recruiting
Physical activity study for women with Behcet's and metabolic syndrome
This study tests if a physical activity program helps women who have both Behcet's disease and metabolic syndrome. It aims to improve their health and well-being.
Giza, DokkiAges 40–50 - NCT07701876Recruiting
Heart failure recovery markers study
This study looks for markers in the blood that can predict whether the heart's pumping function improves in people with chronic heart failure. It may help doctors understand which treatments work best for each person.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07580547Recruiting
Atrial fibrillation ablation: study on sex differences
This research compares how atrial fibrillation (AF) affects men and women differently. If you are having your first catheter ablation for AF and are between 18 and 80, this study may help doctors understand outcomes better.
Be’er Ya‘aqovAges 18–80 - NCT06902896RecruitingPhase 1/Phase 2
FAP iCDC therapy for advanced heart failure from dilated cardiomyopathy
This trial tests a new treatment called FAP iCDC for people with end-stage dilated cardiomyopathy, a type of heart muscle disease. It aims to see if this therapy is safe and helps improve heart function when standard medicines are no longer enough.
Hangzhou, ZhejiangAges 18–75 - NCT07702968Recruiting
Low-field MRI for stroke patients in the ER
This trial uses a low-field MRI machine to scan the brains of people with suspected stroke who come to the emergency room. It aims to see if this type of MRI can help doctors make faster and better decisions about treatment.
Leiden, South HollandAges 18 years+ - NCT07492498Recruiting
Atrial fibrillation care program to prevent heart failure in rural China
This trial tests a new way of caring for older adults with atrial fibrillation (irregular heartbeat) in rural villages to help prevent heart failure. Trained village doctors will use telemedicine (remote healthcare) to manage your condition.
Yancheng, DongtaiAges 65–80 - NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
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- Immune system & allergy
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- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.