Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT06931509Recruiting
How vision and body sense work after stroke
This study looks at how your brain combines what you see with what you feel in your body after a stroke. It may help understand how these senses work together to guide movement.
Saint-Etienne, FranceAges 18–80 - NCT07392801Recruiting
Study on AGE accumulation in long-term parenteral nutrition patients
This study looks at how certain compounds called AGEs build up in the body of people who rely on long-term parenteral nutrition (nutrition given through a vein). It aims to understand whether this affects health and to find better ways to monitor patients.
BordeauxAges Any age - NCT07561034Recruiting
Home Exercise Program for Pulmonary Hypertension and Lung Disease
This study tests whether daily home exercises can help people with pulmonary hypertension (high blood pressure in the lungs) combined with interstitial lung disease (scarring of lung tissue). Researchers will send you daily messages to support your exercise routine and see if it improves your symptoms and quality of life.
Rochester, New YorkAges 18 years+ - NCT06311773Enrolling by invitation
Testing the Boomerang Catheter for severe leg artery disease
This trial tests a new device called the Boomerang Catheter for people with severe leg artery disease (CLTI) who have no other treatment options to save their limb. The goal is to see if this catheter can restore enough blood flow to help the leg heal.
San Bernardino, CaliforniaAges 18 years+ - NCT06597006RecruitingPhase 3
Study of inclisiran for children with homozygous familial high cholesterol
This trial tests a new medicine called inclisiran to lower very high cholesterol in children aged 2 to 12 who have a specific genetic condition (homozygous familial hypercholesterolemia, or HoFH). You may not need to change your current cholesterol treatments, and the study will check if inclisiran can help reduce your LDL cholesterol further.
San Francisco, CaliforniaAges 2–11 - NCT06779630Recruiting
Study of a 48mm drug-coated stent for long coronary artery blockages
This trial tests a longer-than-usual drug-coated stent (Orsiro Mission) for treating long blockages in heart arteries. It aims to see if the stent is safe and effective for people with coronary artery disease.
Concord, CaliforniaAges 18 years+ - NCT06547827Recruiting
Robot-assisted rehab for stroke recovery
This study compares standard rehabilitation with therapy that uses robots and other digital tools to help people regain movement after a stroke. It's for people who had a first stroke within the last 6 months and have some arm, leg, or balance problems.
AcerenzaAges 18 years+ - NCT07724184Recruiting
Treating calcified heart arteries with a stent
This trial tests a way to treat hardened, calcified heart artery blockages using a stent. It may help people who have moderate blockages that haven't been treated before.
AalborgAges 18–90 - NCT07722910Recruiting
Iris blood flow in diabetic neovascular glaucoma
This study uses a special camera (OCTA) to look at blood flow in the iris of people with or without type 2 diabetes and diabetic neovascular glaucoma. The goal is to understand how blood flow changes in this eye condition.
Jinan, ShandongAges 18 years+ - NCT07724171Recruiting
Long-term results after PFO closure surgery
This study looks at how well patients do over time after having a hole in their heart (patent foramen ovale, or PFO) closed with a small device inserted through a vein. It may help doctors understand the benefits and risks of the procedure.
SeoulAges 19 years+ - NCT07721701Recruiting
Digital Dementia Registry for Bavaria
This study follows people with mild cognitive impairment or dementia and their family caregivers over time. It aims to learn more about how these conditions progress and how to improve care, especially for those living in Bavaria.
AschaffenburgAges Any age - NCT07045194Recruiting
Study of Virtue balloon for coronary stent re-narrowing
This trial tests a special balloon to treat narrowed areas inside a previously placed heart stent. It may help by reopening the artery without adding another stent.
Gainesville, FloridaAges 18 years+ - NCT06183684Recruiting
Study of a new tricuspid valve replacement for severe leakage
This study tests a new, less invasive way to replace the tricuspid valve (the valve between the right upper and lower heart chambers) in people with severe leakage. The valve is delivered through a vein in the neck or leg, avoiding open-heart surgery.
Tucson, ArizonaAges 18–90 - NCT06506942Recruiting
TRICURE device study for leaky heart valve
This study tests a new device to help people with severe tricuspid regurgitation (leaky heart valve) who are at higher risk from surgery. It aims to see if the device can reduce the leak and improve symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT06910670Recruiting
Web tool for cancer treatment decisions
This trial tests a web-based tool to help people with certain cancers make treatment decisions. It is for patients already enrolled in a related study at Washington University.
St Louis, MissouriAges 18 years+ - NCT06072482RecruitingPhase 4
Avacopan for ANCA vasculitis (GPA or MPA)
This study tests an oral medication called avacopan for people with active ANCA-associated vasculitis (GPA or MPA). It’s for those who need strong treatment to control their disease and aims to see if avacopan works as well as standard therapies.
Anchorage, AlaskaAges 18–100 - NCT07324837RecruitingPhase 3
Study of a clot-busting drug for stroke up to 24 hours later
This trial tests a single dose of a new clot-dissolving medicine for people who had a stroke 4.5 to 24 hours ago. It may help if you cannot have standard treatments like a clot-removal procedure or other clot-busting drugs.
Ryazan, Ryazan OblastAges 18 years+ - NCT07664189Enrolling by invitation
Left bundle pacing plus CRT vs. LBBP alone
This trial tests a new pacing approach that combines a left bundle branch pacemaker with standard cardiac resynchronization therapy (CRT) for people with heart failure. It aims to improve the heart's pumping efficiency compared to using the left bundle branch pacemaker alone.
Medellín, AntioquiaAges 18 years+ - NCT05079399Recruiting
Diabetic eye screening study using eye scans
This study looks for specific eye findings (“biomarkers”) in people with type 2 diabetes using eye imaging. It may help researchers better understand diabetic retinopathy and how to detect it earlier or more accurately.
Carmel, IndianaAges 18 years+ - NCT07711457Recruiting
Extended reality to guide brain bypass surgery
This trial tests whether extended reality (XR) technology can help surgeons more precisely plan and perform bypass surgery for people with moyamoya disease or blocked carotid arteries. It may make the procedure safer and more effective.
TaipeiAges 18–85 - NCT05701917Recruiting
Clot-busting device versus blood thinners for leg clot
This study compares a clot-removal device (ClotTriever) plus standard care versus standard blood thinners alone for a deep vein clot in the leg. It aims to see which approach better improves leg symptoms and outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT02744677Recruiting
Pulmonary valve procedure to improve blood flow issues
This trial studies a transcatheter pulmonary valve (a valve placed through a catheter) in people whose right-sided outflow tract valve/conduit is not working well. It aims to improve blood flow and reduce pressure problems, while checking safety and results after the procedure.
Birmingham, AlabamaAges Any age - NCT07215195Recruiting
Brain injury, sleep, and mental health study
This study looks at how brain injuries affect sleep and mental health in the months after injury. It is for people who have had a stroke, brain bleed, or traumatic brain injury within the past year and are willing to let the research team contact their doctor if needed.
OxfordAges 18 years+ - NCT07240831Recruiting
Blood pressure monitor trial for people with or without irregular heartbeat
This trial tests a small chest patch that measures blood pressure without a cuff, using a light sensor. It is designed for people who need 24-hour blood pressure monitoring, including those with atrial fibrillation or atrial flutter.
Birmingham, AlabamaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.