Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT04630873RecruitingPhase 1
Botox dilution options for walking in hemiplegic gait
This Phase 1 study tests whether using a lower or higher dilution of Botox injections improves walking in people with hemiplegic gait. The goal is to see which dilution works better (and is safe) for walking and leg stiffness.
IoanninaAges 18 years+ - NCT06718075Recruiting
Comparing tools to predict stroke risk after a mini-stroke
This study looks at two ways to estimate your chance of having a stroke after a transient ischemic attack (a mini-stroke). You will be asked some questions, and your risk will be calculated using both methods. The goal is to see which tool is more accurate for patients like you.
BolognaAges 18 years+ - NCT03457168Recruiting
Testing treatment for high blood pressure during sleep
This study looks at how to manage high blood pressure specifically during sleep, aiming to lower the risk it can cause over time. It may help you if your blood pressure readings stay high at night even if you’re otherwise able to function normally.
Ourense, OrenseAges 18 years+ - NCT04117230Recruiting
Registry for heart support devices after severe circulation problems
This study is a registry that collects information from adults who need a temporary heart circulation support device such as VA-ECMO or an Impella pump (or newer similar devices). It may help doctors better understand which patients benefit most and how these devices are used in real life.
BaselAges 18 years+ - NCT04469517Recruiting
Study of low-oxygen factors in hereditary bleeding disorder
This study looks at how “low-oxygen” signals may affect people with hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder. It may help researchers understand what drives symptoms and could guide future treatments.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT05203003Recruiting
Testing whether measurable cancer leftovers predict outcomes
This study looks at whether small leftover signs of multiple myeloma in blood or bone marrow (called measurable residual disease, or MRD) can predict how well treatment works. It involves people already taking study treatment in a larger trial and checks results about two years later to see who benefits most.
ParisAges 18 years+ - NCT05625438Recruiting
Home video therapy for early arm recovery after stroke
This study tests a home-based (telerehabilitation) program to help people practice arm movement after a recent stroke (or certain brain injuries). It may help improve arm function when started soon after symptoms begin.
Fullerton, CaliforniaAges 18 years+ - NCT07593794Recruiting
Quality of Recovery After Heart Surgery Study
This study measures how well patients recover after planned heart surgery by having them answer questions about their physical and emotional wellbeing. The goal is to understand what affects recovery so doctors can better support patients afterward.
KocaeliAges 18 years+ - NCT07591298RecruitingPhase 2
SYH2070 injection for homozygous familial high cholesterol
This study tests a new injectable medication (SYH2070) designed to lower cholesterol in people with homozygous familial hypercholesterolemia—a genetic condition that causes extremely high cholesterol levels despite treatment. The goal is to see if this drug safely reduces cholesterol better than current options.
Changsha, HunanAges 18 years+ - NCT07589452Recruiting
Pacemaker heart rate settings and blood pressure in older adults
This study tests whether a specific pacemaker heart-rate setting helps control blood pressure and improve heart function in adults over 65 with slow heartbeats and high blood pressure. You would receive a dual-chamber pacemaker (a standard treatment) and be monitored to see how the rate setting affects your health.
Taiyuan, ShanxiAges 65 years+ - NCT07586995Recruiting
Safety and performance study of the TriClip heart valve repair device
This study tracks how well the TriClip device works and how safe it is after it's placed in your heart to repair a leaky valve. You'll attend follow-up visits so doctors can monitor your recovery and device function over time.
Phoenix, ArizonaAges 18 years+ - NCT07588100RecruitingPhase 1
Safety study of RO7663498 eye injection for diabetic retinopathy
This is an early-stage safety study testing a new medicine injected directly into the eye to treat diabetic retinopathy (damage to blood vessels in the retina caused by diabetes). The study checks if the medicine is safe and how the body processes it.
Glendale, CaliforniaAges 18 years+ - NCT07589634RecruitingPhase 2
Tocilizumab to prevent side effects from ramantamig in multiple myeloma
This study tests whether a drug called tocilizumab can prevent serious side effects (cytokine release syndrome) when combined with a new cancer drug called ramantamig. You'll be eligible if you have multiple myeloma that has come back or stopped responding to prior treatments.
Goodyear, ArizonaAges 18 years+ - NCT05906056Recruiting
CPM therapy vs bone overgrowth in hip or knee
This study compares continuous passive motion (a machine that gently moves a joint without you moving it) versus the body’s tendency to form extra bone called heterotopic ossification. It aims to see whether CPM can affect how and how much bone overgrowth develops after neurologic injuries like stroke, brain injury, or spinal cord injury.
Ioannina, EpirusAges 15–70 - NCT06700395RecruitingPhase 1
Study of TQB2029 for multiple myeloma patients
This trial tests a new injectable drug, TQB2029, for people with multiple myeloma. It aims to see if the drug is safe and effective, and may be an option if you have measurable disease and are in relatively good health.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07588503RecruitingPhase 1
FES Cycling With Blood Flow Restriction for Spinal Cord Injury
This study tests a new exercise method combining electrical stimulation (FES) and controlled blood flow restriction while you cycle. It's designed to improve heart health, blood sugar control, and fitness in people with spinal cord injuries.
Toronto, OntarioAges 18–75 - NCT07587294Recruiting
Ultrasound Treatment to Prevent Heart Rhythm Problems After Heart Attack
This trial tests whether a special ultrasound procedure on the side of your neck can help prevent dangerous irregular heartbeats in patients who recently had a heart attack treated with a stent. The goal is to see if this treatment is safe and effective.
Huangshi, HubeiAges 18–80 - NCT07587437Enrolling by invitation
Magnetic Camera Exam Before Weight-Loss Surgery
This study tests a swallowable magnetic camera to examine your stomach and small intestine before bariatric (weight-loss) surgery. The camera may help doctors plan your surgery and catch any issues beforehand.
Cleveland, OhioAges 18 years+ - NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Cotignola, RavennaAges 18 years+ - NCT07588997Recruiting
Brain Training After Aneurysm Bleeding to Improve Thinking and Movement
This study tests whether combining thinking exercises with physical movements can help people recover better after a brain aneurysm ruptures and bleeds. You'd start the training early in your recovery (2-7 days after treatment) to see if it helps your memory, attention, and ability to move.
TaipeiAges 18 years+ - NCT07588256Recruiting
AI Digital Health Platform for High Blood Pressure and Related Conditions
This study uses artificial intelligence and a digital health app to help manage high blood pressure, high cholesterol, diabetes, kidney disease, and heart disease. It aims to help people track their health at home and receive better care recommendations through technology.
New Taipei CityAges Any age - NCT07594704Recruiting
Comparing catheter placement methods for long-term IV access
This study compares two different techniques for placing a special long IV catheter (PICC) in your arm. The catheter stays in place for weeks or months to deliver medications or fluids. Researchers want to see which placement method works better and causes fewer problems.
Guangzhou, GuangdongAges 18–75 - NCT07589855Recruiting
Touch therapy for neglect awareness after stroke
This study tests whether regular touch-based therapy can help stroke survivors who ignore one side of their body (called unilateral neglect). You would receive therapy sessions, likely at home, to see if this treatment improves your awareness and function.
Newcastle-under-LymeAges 18 years+ - NCT07588932RecruitingEarly Phase 1
Medication and Robot Training for Stroke Arm Recovery
This study tests whether three medications (Telmisartan, Cilostazol, and Metformin) combined with robotic arm training can help people improve arm movement and strength after a chronic stroke. You would participate in supervised training sessions using a robotic rehabilitation system.
Charlestown, MassachusettsAges 21–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.