Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT05153967Recruiting
Study late effects after sickle cell curative treatments
This study looks at long-term health effects after curative treatments for sickle cell disease, such as bone marrow transplant. Your participation helps researchers understand what changes over time after treatment, and what might need monitoring or care.
Washington D.C., District of ColumbiaAges 4–65 - NCT05135351Recruiting
Prebiotics to help your gut health after cancer cell treatment
This trial tests whether taking prebiotics (food for helpful gut bacteria) can improve gut microbiome diversity after your own cancer-cell treatment, like autologous stem cell transplant or CAR-T. It may help your gut ecosystem recover during and after therapy.
Omaha, NebraskaAges 19 years+ - NCT07350499Recruiting
Using Symphony or Prodigy to remove blood clots
This study tests how well the Symphony or Prodigy system works for removing blood clots from arteries or veins. You may qualify if you are 18 or older and scheduled for a procedure that uses one of these devices.
Huntsville, AlabamaAges 18 years+ - NCT07654426RecruitingPhase 2
Heart protection during lymphoma chemotherapy
This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.
Boston, MassachusettsAges 18 years+ - NCT06494878RecruitingPhase 3
Aspirin after childbirth to prevent blood clots
This trial tests if taking aspirin after delivery helps prevent dangerous blood clots in women with certain risk factors. It's for new mothers who have a clotting disorder, were on bed rest, or have multiple other risk factors like high weight or preeclampsia.
BrusselsAges 18 years+ - NCT07717723Recruiting
Support for caregivers of heart disease patients
This study tests a program to help caregivers of people with heart disease manage stress and challenges. It aims to support your mental health while caring for a loved one.
Sacramento, CaliforniaAges 18 years+ - NCT06931821Recruiting
Mapping to guide ablation for ventricular tachycardia
This study tests a new way to map the heart's electrical activity to guide a procedure that destroys the tissue causing fast, dangerous heart rhythms. It's for people with heart disease and ventricular tachycardia that hasn't been controlled by medication.
Phoenix, ArizonaAges 18 years+ - NCT05511246RecruitingPhase 2
Alcohol injection for fast heart rhythm
This trial tests injecting ethanol (alcohol) into a vein near the heart to treat a dangerous fast heart rhythm called ventricular tachycardia. It may be an option for people who have an implanted defibrillator and have not found relief with other treatments.
Houston, TexasAges 18–85 - NCT07724925Recruiting
Comparing two arm therapies for stroke recovery
This study compares two types of arm and hand therapy for people recovering from a stroke. It aims to see which approach helps improve arm function and daily living skills.
Nankana SahibAges 45–70 - NCT07726056Recruiting
Heart ablation in athletes with atrial fibrillation
This trial tests if a heart procedure (cardiac ablation) helps endurance athletes who have atrial fibrillation (an irregular heartbeat) perform better in sports. Athletes will track their training data before and after the procedure to see if their performance improves.
MelbourneAges 18–80 - NCT07724899Recruiting
A new ablation treatment for atrial fibrillation
This study tests a new type of ablation (pulsed field ablation) for people with atrial fibrillation who haven't gotten enough relief from medication alone. It aims to see if isolating the superior vena cava along with the pulmonary veins is safe and effective.
Chengdu, SichuanAges 18 years+ - NCT04686097Recruiting
Comparing two treatments for leg vein problems
This trial compares a needle-based procedure (electrocoagulation) with a foam injection (sclerosing foam) to treat faulty veins in the legs that cause skin damage or ulcers. It aims to find which method works better for people with moderate to severe vein disease.
Hefei, AnhuiAges 18–80 - NCT07725003Recruiting
Home-based rehab program vs. standard physical therapy for stroke recovery
This study compares a home-based motor relearning program with standard physical therapy delivered through video calls, to see which helps stroke survivors improve movement and function better. It may be a good option if you had a stroke 3 to 12 months ago and have access to a device with internet.
Faisalabad, Punjab ProvinceAges 40–70 - NCT07359898Recruiting
Study of a new heart valve for aortic stenosis
This study is testing a new type of heart valve (Navitor or Navitor Vision) for people with aortic stenosis. The valve is placed without open-heart surgery, and the goal is to see how well it works in a real-world setting. If you've already been recommended for this procedure by your heart team, you may be able to join.
San Donato Milanese, LombardyAges 18 years+ - NCT07725471Recruiting
Comparing breathing and neck release in stroke recovery
This study compares two gentle therapy techniques—special breathing exercises and a hands-on release at the base of the skull—to see which helps stroke survivors with one-sided weakness regain movement and breathing. It may be a good fit if you're still recovering from a first stroke months ago and don't have major heart or lung problems.
AfyonkarahisarAges 18–84 - NCT07726017Recruiting
Balance and walking exercises for chronic stroke recovery
This study compares two types of walking and balance exercises for people who had a stroke 6 to 12 months ago. It aims to see which type of practice helps improve balance and walking best.
SialkotAges 40–70 - NCT07725250Recruiting
AI-guided blood pressure trial for stage I-II hypertension
This study tests whether combining artificial intelligence with personalized medicine can help lower blood pressure in people with stage I or II hypertension (140/90 or higher). If you have high blood pressure and can walk without help, this trial may be for you.
La Jolla, CaliforniaAges 18 years+ - NCT07726901Recruiting
Comparing Two Ablation Methods for Persistent Atrial Fibrillation
This study compares two techniques for treating persistent atrial fibrillation: one uses standard anatomy-based ablation, and the other uses a special mapping system to guide the procedure. It aims to find which method works better for people who have not had prior ablation.
Seoul, SeoulAges 19 years+ - NCT07724730Recruiting
Moving with and without music after a stroke
This study compares two types of movement practice for people recovering from a recent stroke. One group will do everyday tasks like walking and reaching, and the other will do the same movements but with a rhythmic beat to help with timing and coordination.
Daska KalanAges 40–60 - NCT07140211RecruitingPhase 3
Low-dose heparin to prevent blood clots after childbirth
This trial is testing a short course of a low-dose blood thinner (heparin) to prevent dangerous blood clots in the legs or lungs after childbirth. It is for women who have certain risk factors that make clots more likely.
BadenAges 18 years+ - NCT06251713Recruiting
Fluid removal guided by VeXUS score after heart surgery
This trial tests if using a special ultrasound score (VeXUS) to guide fluid removal can improve recovery in patients with acute kidney injury after heart surgery. It compares this approach to standard care to see if it leads to better outcomes.
Bron, BronAges 18–85 - NCT07291427Recruiting
Coiling for chronic subdural hematoma
This trial tests a procedure called coiling (placing tiny coils) to block the blood supply to a chronic subdural hematoma, a slow-growing blood collection around the brain. It may help reduce the need for surgery and improve recovery.
New York, New YorkAges 18 years+ - NCT07049692Recruiting
Hyperbaric oxygen after stroke clot removal study
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help people recover better after having a stroke caused by a large clot in the front part of the brain. It is for people who recently had a clot removal procedure and have some remaining disability but are still awake and aware.
Beijing, Beijing MunicipalityAges 35–75 - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Valley Village, CaliforniaAges 22 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.