Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Alexander City, AlabamaAges 18–85 - NCT03910569Recruiting
Takotsubo heart event registry and blood protein study
This study enrolls people who have been diagnosed with Takotsubo (a temporary, stress-related heart condition). It aims to better understand Takotsubo by collecting your medical records and analyzing proteins, which may help improve care in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT05650541Recruiting
Testing a home device to help chronic heart failure
This study tests whether a CardioPulmonary Management (CPM) system device used at home is safe and can improve outcomes for people with chronic heart failure. It may help manage symptoms and reduce complications, especially for higher-risk patients.
Palm Springs, CaliforniaAges 18 years+ - NCT05489705Recruiting
Real-world registry for mavacamten and other obstructive HCM treatments
This study collects real-world information about people with obstructive hypertrophic cardiomyopathy (HCM) who are being treated with mavacamten or other standard medicines. It aims to understand patient characteristics, treatment choices over time, and long-term outcomes.
Anchorage, AlaskaAges 18 years+ - NCT04874428RecruitingPhase 1
Blood thinner pills in people with mild-to-moderate cirrhosis
This early study tests whether the blood thinner pills rivaroxaban and apixaban can be used safely in people with liver cirrhosis that is not too severe. It may help doctors understand the safest way to prevent or treat blood clots in this group.
BernAges 18 years+ - NCT07493304RecruitingPhase 3
Preventing blood clots in people with cancer
This trial tests a new anticoagulant medication to treat and prevent blood clots in patients with active cancer. You may qualify if you have a recent clot in your leg or lungs and are already taking a blood thinner.
Hialeah, FloridaAges 18 years+ - NCT06658730Recruiting
A study to check long-term safety of a Gore thoracic stent graft
This registry study tracks patients who have or will receive a Gore thoracic stent graft to see how well the device performs over time. It helps doctors understand the device's long-term benefits and any possible complications.
Tucson, ArizonaAges 18 years+ - NCT07649616Enrolling by invitation
Training Law Enforcement to Use Heart-Restart Devices
This study helps police officers learn to use automated external defibrillators (AEDs)—machines that can restart a stopped heart during cardiac emergencies. The goal is to increase how often these devices are used and improve survival rates when officers respond to cardiac arrest calls.
Detroit, MichiganAges 18 years+ - NCT07218627RecruitingPhase 1
Study of an investigational medicine for heart failure
This study tests an experimental medicine called NNC0537-1482 for people with heart failure. It aims to see if the medicine helps improve symptoms and heart function.
LondonAges 40–75 - NCT07771127Recruiting
Comparing a special pad to a sandbag for groin bleeding after heart procedure
This study compares two ways to stop bleeding after a heart procedure through the groin: using a special pad or a sandbag. It aims to see which method works better and is safer.
Bursa, NilüferAges 18 years+ - NCT07770386Recruiting
Predicting heart trouble after child heart surgery
This study looks at whether a simple blood test can predict a serious heart problem called low cardiac output syndrome after a child has heart surgery. Doctors hope this will help them spot and treat this issue earlier, which could lead to better recovery for your child.
LilleAges Up to 17 years - NCT07771335Recruiting
Erlangen stroke registry: tracking strokes over time
This study collects health information from people in Erlangen, Germany who have had a stroke. It helps researchers understand stroke causes and outcomes to improve future care.
ErlangenAges 18 years+ - NCT06376526RecruitingPhase 2
Immunotherapy treatment for newly diagnosed multiple myeloma
This trial tests an immunotherapy drug combination for people newly diagnosed with multiple myeloma who have had some response to initial treatment but still have signs of disease. The goal is to see if this approach can help eliminate remaining cancer cells and potentially improve outcomes.
Miami, FloridaAges 18 years+ - NCT07769528Recruiting
Heart pump support for severe heart failure
This study tests a device that helps the heart pump blood when it is too weak to do so, even with medicine, after surgery, or while waiting for a transplant. It aims to see if it's safe and works well.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06666673RecruitingEarly Phase 1
Effects of a muscle relaxant on arm movement after stroke
This study looks at how the brain controls arm movements after a stroke. It tests whether a medication called tizanidine, which relaxes muscles, can improve arm function when combined with physical therapy.
Chicago, IllinoisAges 18–80 - NCT07524036Recruiting
Nursing education to help stroke patients follow care plans
This study tests whether a special nursing education session helps stroke patients stick to their recovery plan after going home. The goal is to see if personalized teaching improves how well patients take medications and follow doctor's advice.
BayonneAges 18 years+ - NCT06621329RecruitingPhase 2/Phase 3
Numbing shot for headache after brain bleed
This trial tests a numbing injection inside the nose to quickly relieve severe headaches caused by a brain bleed (subarachnoid hemorrhage). It may help reduce pain without strong medicines.
Sacramento, CaliforniaAges 18–100 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT07094087RecruitingPhase 3
Blood clotting medicine for heart surgery bleeding
This trial tests a medicine called 4F-PCC to stop bleeding during complex heart surgery that uses a heart-lung machine. It could help people who have bleeding problems after the surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06620458Enrolling by invitation
Factors affecting drug-coated balloon restenosis
This study looks at why some drug-coated balloons (used to open blocked heart arteries) might narrow again after treatment. If you have coronary artery disease and are scheduled for this procedure, you may be eligible to help researchers understand what factors affect the balloon's success.
Zhengzhou, ChinaAges 18 years+ - NCT07754240Recruiting
Stent graft for abdominal aortic aneurysm
This trial tests a new stent graft device for treating abdominal aortic aneurysms. The device is placed inside the aneurysm to reinforce the artery and prevent rupture, which may help people who are candidates for this minimally invasive procedure.
PlevenAges 18–80 - NCT07770035Enrolling by invitation
School-age outcomes after newborn brain injury
This study looks at how children who had a brain injury around birth (called hypoxic-ischaemic encephalopathy, or HIE) are doing in school and daily life, compared to children without that history. It aims to understand the long-term effects and support needs.
Cork, CorkAges 5–12 - NCT04859270Recruiting
Rehab support for survivors after cardiac arrest
This study looks at a “whole-person” support plan for people who survived a non-traumatic cardiac arrest. It aims to improve the survivor’s health and also help support family members as they recover.
TaipeiAges 20 years+ - NCT07689591Recruiting
Non-invasive blood flow boost for heart attack patients
This trial tests a non-invasive method to improve blood flow in the arm during a heart attack. It may help reduce heart muscle damage before the standard artery-opening procedure.
Elâzığ, ElaziğAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.